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When is sodium bisulfite too old to use?

Sodium bisulfite has an expiration date because it slowly decomposes over time. The decomposition products can react with other components of the tissue sample, leading to incorrect results.

The expiration date for sodium bisulfite is typically printed on the bottle. However, it is important to note that this date is only an estimate. The actual shelf life of sodium bisulfite can vary depending on the storage conditions.

To extend the shelf life of sodium bisulfite, it should be stored in a cool, dry place. It is also important to keep the container tightly closed.

If you are using sodium bisulfite that is past its expiration date, it is important to test it to make sure that it is still active. This can be done by adding a few drops of sodium bisulfite to a solution of water and iodine. If the solution turns a yellow-brown color, then the sodium bisulfite is still active. If the solution does not change color, then the sodium bisulfite has decomposed and should not be used.

It is important to use fresh sodium bisulfite to ensure that your tissue samples are properly preserved and that your results are accurate.


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